{"id":5535,"date":"2022-09-23T13:45:57","date_gmt":"2022-09-23T11:45:57","guid":{"rendered":"https:\/\/smartcells-hk.empressia.dev\/umbilical_cord_tissue_stem_cells_properties_and_benefits\/"},"modified":"2026-03-05T09:03:12","modified_gmt":"2026-03-05T08:03:12","slug":"umbilical_cord_tissue_stem_cells_properties_and_benefits","status":"publish","type":"post","link":"https:\/\/smartcells.com.hk\/zh-hant\/stem-cells-blog\/umbilical_cord_tissue_stem_cells_properties_and_benefits\/","title":{"rendered":"\u81cd\u5e36\u7d44\u7e54\u5e79\u7d30\u80de\uff1a\u7279\u6027\u8207\u76ca\u8655"},"content":{"rendered":"<p><strong>\u83ef\u901a\u6c0f\u81a0\u8cea<\/strong><strong>(Wharton\u2019s Jelly)<\/strong><\/p>\n<p>\u81cd\u5e36\u662f\u5e7e\u4e4e\u6240\u6709\u54fa\u4e73\u52d5\u7269\uff08\u5305\u62ec\u4eba\u985e\uff09\u7684\u6bcd\u9ad4\u5167\uff0c \u80ce\u5152\u8207\u61f7\u5b55\u7684\u6bcd\u89aa\u7684\u80ce\u76e4\u7684\u4e00\u7a2e\u806f\u7e6b\u7d50\u69cb\u3002<\/p>\n<p>\u81cd\u5e36\u72c0\u5982\u7e69\u7d22\uff0c\u8868\u9762\u5149\u6ed1\u900f\u660e\uff0c\u5167\u542b\u7d50\u7de0\u7d44\u7e54\u548c\u8840\u7ba1\uff1b\u5728\u80ce\u76e4\u5167\u80ce\u5152\u7684\u8840\u6db2\u5faa\u74b0\u8207\u6bcd\u89aa\u7684\u8840\u6db2\u5faa\u74b0\u4ea4\u63db\u71df\u990a\u7269\u8cea\u548c\u6c27\u6c23\uff0c\u901a\u904e\u81cd\u5e36\u71df\u990a\u7269\u8cea\u8207\u6c27\u6c23\u4f86\u5230\u6b63\u5728\u6210\u9577\u7684\u80ce\u5152\u7684\u9ad4\u5167\u3002<\/p>\n<p>\u4e00\u822c\u4eba\u7684\u81cd\u5e36\u542b\u6709\u4e09\u689d\u8840\u7ba1\uff1a\u5169\u689d\u81cd\u52d5\u8108\u548c\u4e00\u689d\u81cd\u975c\u8108\u3002<\/p>\n<p>\u5169\u689d\u52d5\u8108\u5c07\u4e8c\u6c27\u5316\u78b3\u548c\u71df\u990a\u5c11\u7684\u8840\u8f38\u5165\u80ce\u76e4\uff0c\u975c\u8108\u5c07\u6c27\u6c23\u548c\u71df\u990a\u8c50\u5bcc\u7684\u8840\u6db2\u8f38\u56de\u80ce\u5152\u3002\u53e6\u4e00\u689d\u52d5\u8108\u5728\u80ce\u5152\u7684\u7b2c\u4e00\u5468\u5c31\u9000\u5316\u4e86\u3002\u52d5\u8108\u8f38\u9001\u975c\u8108\u8840\uff08\u5bcc\u542b\u4e8c\u6c27\u5316\u78b3\u548c\u5ee2\u7269\u7684\u8840\uff09\u3001\u975c\u8108\u8f38\u9001\u52d5\u8108\u8840\uff08\u5bcc\u542b\u6c27\u6c23\u548c\u71df\u990a\u7684\u8840\uff09\u7684\u8840\u7ba1\u9664\u80ba\u52d5\u8108\/\u975c\u8108\u5916\u5c31\u53ea\u6709\u81cd\u52d5\u8108\/\u975c\u8108\u3002\u4eba\u7684\u81cd\u5e36\u7d0450\u81f360\u5398\u7c73\u9577\uff0c\u76f4\u5f91\u7d042\u5398\u7c73\uff0c\u81cd\u5e36\u5167\u7684\u8840\u7ba1\u7531\u83ef\u901a\u6c0f\u81a0\u8cea\uff08Wharton&#8217;s Jelly\uff09\u5305\u88f9\uff0c\u83ef\u901a\u6c0f\u81a0\u8cea\u4e2d\u542b\u6709\u8c50\u5bcc\u7684\u5e79\u7d30\u80de\u3002<\/p>\n<p>\u901a\u904e\u80ce\u76e4\u7d68\u6bdb\u4e0a\u76ae\u7684\u6ef2\u900f\u4f5c\u7528\uff0c\u80ce\u5152\u8840\u6db2\u65bc\u7d68\u6bdb\u9593\u9699\u5167\uff0c\u8207\u6bcd\u9ad4\u8840\u6db2\u4e4b\u9593\u9032\u884c\u7269\u8cea\u7684\u4ea4\u63db \u3002<\/p>\n<p>\u80ce\u5152\u9038\u51fa\u5f8c\u81cd\u5e36\u5931\u53bb\u4f5c\u7528\uff0c\u6578\u5206\u9418\u5167\u640f\u52d5\u505c\u6b62\uff0c\u6b64\u6642\u61c9\u5728\u81cd\u5e36\u6839\u90e8\u5c07\u5176\u526a\u65b7\u4e26\u7d50\u7d2e\uff0c\u52d5\u7269\u4e00\u822c\u662f\u6bcd\u52d5\u7269\u5c07\u81cd\u5e36\u54ac\u65b7\u3002\u4e4b\u5f8c\u5269\u9918\u7684\u81cd\u5e36\u6b98\u6bb5\u5728\u4e00\u5230\u5169\u5468\u5167\u812b\u843d\uff0c\u7559\u4e0b\u7684\u75a4\u75d5\u5c31\u662f\u809a\u81cd\u3002<\/p>\n<p>\u5b30\u5152\u51fa\u751f\u5f8c\u907a\u7559\u5728\u80ce\u76e4\u548c\u81cd\u5e36\u4e2d\u662f\u5e79\u7d30\u80de\u7684\u91cd\u8981\u4f86\u6e90\uff0c\u5176\u4e2d\u7814\u7a76\u8207\u81e8\u5e8a\u4e0a\u591a\u63a1\u7528\u4f86\u6e90\u81ea\u81cd\u5e36\u4e4b\u83ef\u901a\u6c0f\u81a0\u8cea\u70ba\u9593\u8cea\u5e79\u7d30\u80de\u91cd\u8981\u4f86\u6e90\u3002<\/p>\n<p>\u83ef\u901a\u6c0f\u81a0\u8cea\u9593\u8cea\u5e79\u7d30\u80de(Wharton&#8217;s jelly MSC, WJMSC)\uff0c\u66f4\u5177\u6709\u8f03\u6613\u65bc\u5206\u96e2\u8207\u57f9\u990a\u53ca\u9ad4\u5916\u589e\u751f\u901f\u5ea6\u8f03\u5feb\u7684\u7279\u6027\u3002\u5728\u9ad4\u5916\u8a66\u9a57\u4e5f\u53ef\u4ee5\u6210\u529f\u7684\u8a98\u5c0e\u5206\u5316\u6210\u8102\u80aa\u7d30\u80de\u3001\u8edf\u9aa8\u7d30\u80de\u3001\u786c\u9aa8\u7d30\u80de\u7b49\u3002<\/p>\n<p>WJMSC\u7d93 \u7531 \u8868 \u9762 \u6297 \u539f \u5206 \u6790\u5176\u5177\u6709CD45(-)\u3001CD 34(-)\u3001HLA class II (-) \u3001 C D 7 3 ( + ) \u3001CD90(+) \u3001 CD105(+) \u53ca HLA ABC(+)\u4e4b\u8868\u73fe\u7684\u9593\u8cea\u5e79\u7d30\u80de\u7684\u7279\u6027\uff0c\u4e26\u53ef\u5728\u9ad4\u5916\u8a66\u9a57\u6210\u529f\u7684\u8a98\u5c0e\u5206\u5316\u6210\u8102\u80aa\u7d30\u80de\u3001\u8edf\u9aa8\u7d30\u80de\u53ca\u786c\u9aa8\u7d30\u80de\u3002<\/p>\n<p>\u9593\u8cea\u5e79\u7d30\u80de(MSCs)\u591a\u91cd\u5206\u5316\u6f5b\u80fd\uff0c\u4e0d\u4f46\u6539\u8b8a\u4e86\u4eba\u5011\u539f\u5148\u5c0d\u65bc\u6210\u9ad4\u5e79\u7d30\u80de\u5206\u5316\u80fd\u529b\u53d7\u9650\u7684\u770b\u6cd5\uff0c\u4e5f\u5927\u5e45\u63d0\u5347\u4e86 MSCs\u5728\u7d30\u80de\u7642\u6cd5(cell therapy)\u3001\u7d44\u7e54\u5de5\u7a0b (tissue engineering)\u3001\u53ca\u518d\u751f\u91ab\u5b78(regenerative medicine)\u7b49\u9818\u57df\u7684\u7814\u7a76\u8207\u61c9\u7528\u7684\u50f9\u503c\u3002<\/p>\n<p><strong>\u81cd\u5e36\u9593\u8cea\u5e79\u7d30\u80de<\/strong><strong>(mesenchymal stem cells, MSCs)<\/strong><\/p>\n<p>\u9593\u8cea\u5e79\u7d30\u80de\u662f\u4e00\u985e\u8d77\u6e90\u65bc\u65e9\u671f\u4e2d\u80da\u5c64\uff0c\u4e26\u4e14\u80fd\u5920\u81ea\u6211\u66f4\u65b0\u548c\u5177\u6709\u591a\u5411\u5206\u5316\u6f5b\u80fd\u7684\u6210\u9ad4\u5e79\u7d30\u80de\u3002\u5927\u91cf\u7684\u7814\u7a76\u8b49\u660e\uff0cMSCs \u5728\u518d\u751f\u91ab\u5b78\u9818\u57df\u4e2d\u5177\u6709\u5de8\u5927\u6f5b\u529b,\u672a\u4f86\u53ef\u88ab\u7528\u65bc\u6cbb\u7642\u591a\u7a2e\u985e\u578b\u75be\u75c5,\u5982\u810a\u9ad3\u640d\u50b7\u3001\u809d\u640d\u50b7\u3001\u814e\u640d\u50b7\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7b49\u3002 MSCs \u4e00\u822c\u4f86\u6e90\u65bc\u80ce\u76e4\u3001\u8102\u80aa\u3001\u7259\u9ad3\u3001\u9aa8\u9ad3\u4ee5\u53ca\u81cd\u5e36\u548c\u80ce\u5152\u5167\u81df\u7b49\u5668\u5b98\u7d44\u7e54\u3002\u5176\u4e2d\uff0c\u81cd\u5e36\u4f5c\u70ba\u5728\u6bcd\u9ad4\u548c\u80ce\u5152\u4e4b\u9593\u904b\u8f38\u71df\u990a\u7269\u8cea\u7684\u7d10\u5e36\uff0c\u540c\u6a23\u542b\u6709\u5927\u91cf\u7684\u9593\u8cea\u5e79\u7d30\u80de\u3002\u4e26\u4e14\u76f8\u8f03\u65bc\u6613\u53d7\u4f9b\u9ad4\u7684\u5e74\u9f61\u56e0\u7d20\u5f71\u97ff\u7684\u9aa8\u9ad3\u9593\u8cea\u5e79\u7d30\u80de\u548c\u6613\u53d7\u5230\u91ab\u5b78\u502b\u7406\u9650\u5236\u7684\u80da\u80ce\u4f86\u6e90\u7684\u9593\u8cea\u5e79\u7d30\u80de\u800c\u8a00\uff0c\u589e\u6b96\u6548\u7387\u9ad8\u3001\u4f9b\u9ad4\u5ee3\u6cdb\u3001\u75c5\u6bd2\u611f\u67d3\u7387\u4f4e\u7684\u81cd\u5e36\u9593\u8cea\u5e79\u7d30\u80de(human umbilical cord mesenchymal stem cells,hUCMSCs)\u53ef\u80fd\u662f\u81e8\u5e8a\u61c9\u7528\u6642\u7684\u66f4\u597d\u7684\u9078\u64c7\uff0c\u9019\u4e9b\u512a\u52e2\u4e5f\u4f7f\u5f97 hUCMSCs \u5728\u518d\u751f\u91ab\u5b78\u9818\u57df\u5099\u53d7\u95dc\u6ce8\u3002<\/p>\n<p>\u60f3\u4e86\u89e3\u66f4\u591a? \u8acb\u7559\u4e0b\u8cc7\u6599\u8b93\u6211\u5011\u5c07\u5c0f\u518a\u5b50\u96fb\u90f5\u7d66\u4f60\u3002<\/p>\n<h5><strong><u>\u514d\u8cbb\u7d22\u53d6\u5c0f\u518a\u5b50<\/u><\/strong><\/h5>\n<p>[gravityform id=&#8221;4&#8243; title=&#8221;false&#8221; description=&#8221;true&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n<ul>\n<li><em>Arno, A., Amini-Nik, S., Blit, P., Al-Shehab, M., Belo, C., &amp; Herer, E. et al. (2014). Human Wharton\u2019s jelly mesenchymal stem cells promote skin wound healing through paracrine signaling. Stem Cell Research &amp; Therapy, 5(1), 28.\u00a0<\/em><\/li>\n<li><em>Cheng, T., Yang, B., Li, D., Ma, S., Tian, Y., &amp; Qu, R. et al. (2015). Wharton\u2019s Jelly Transplantation Improves Neurologic Function in a Rat Model of Traumatic Brain Injury. Cellular And Molecular Neurobiology, 35(5), 641-649.\u00a0<\/em><\/li>\n<li><em>Dasari, V. (2014). Mesenchymal stem cells in the treatment of spinal cord injuries: A review. World Journal Of Stem Cells, 6(2), 120.\u00a0<\/em><\/li>\n<li><em>Dazzi, F., &amp; Horwood, N. (2015). Potential of mesenchymal stem cell therapy.\u00a0 &#8211; PubMed &#8211; NCBI. Ncbi.nlm.nih.gov.\u00a0<\/em><\/li>\n<li><em>Kim, N., &amp; Cho, S. (2013). Clinical applications of mesenchymal stem cells. Korean J Intern Med, 28(4), 387.\u00a0<\/em><\/li>\n<li><em>Mitchell, K., Weiss, M., Mitchell, B., Martin, P., Davis, D., &amp; Morales, L. et al. (2003). Matrix Cells from Wharton&#8217;s Jelly Form Neurons and Glia. STEM CELLS, 21(1), 50-60.PrNewswire,. (2015). Beike Biotechnology Publishes New Research Finding Adult Mesenchymal Stem Cells Safe and Effective in Acute Myocardial Infarction. Prnewswire.com.\u00a0<\/em><\/li>\n<li><em>Ramsden, C., Powner, M., Carr, A., Smart, M., da Cruz, L., &amp; Coffey, P. (2013). Stem cells in retinal regeneration: past, present and future. Development, 140(12), 2576-2585.\u00a0\u00a0<\/em><\/li>\n<li><em>Stemcelldigest.com,. (2013). Scientists grow artificial skin using stem cells from the umbilical cord | Stem Cell News Digest. Stemcellnewsdigest.com.\u00a0<\/em><\/li>\n<li><em>Tanna, T., &amp; Sachan, V. (2015). Mesenchymal stem cells: potential in treatment of neurodegenerative diseases.\u00a0 &#8211; PubMed &#8211; NCBI. Ncbi.nlm.nih.gov.\u00a0<\/em><\/li>\n<li><em>Volarevic, V., Nurkovic, J., Arsenijevic, N., &amp; Stojkovic, M. (2014). Concise Review: Therapeutic Potential of Mesenchymal Stem Cells for the Treatment of Acute Liver Failure and Cirrhosis. STEM CELLS, 32(11), 2818-2823.\u00a0\u00a0<\/em><\/li>\n<li><em>Verter, D. (2015). Parent&#8217;s Guide to Cord Blood. Parentsguidecordblood.org. Retrieved 26 October 2015, f<\/em><\/li>\n<li><em>Watson, N., Divers, R., Kedar, R., Mehindru, A., Mehindru, A., Borlongan, M., &amp; Borlongan, C. (2015). Discarded Wharton jelly of the human umbilical cord: a viable source for mesenchymal stromal cells. Cytotherapy, 17(1), 18-24.\u00a0<\/em><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u4e16\u754c\u5404\u5730\u9802\u5c16\u79d1\u5b78\u5bb6\u7684\u5831\u544a\u5747\u986f\u793a\u81cd\u5e36\u4e2d\u7684\u83ef\u901a\u6c0f\u81a0\u8cea (Wharton\u2019s Jelly\uff0c\u4e00\u7a2e\u65bc\u81cd\u5e36\u5167\u7684\u81a0\u72c0\u7d44\u7e54) \uff0c\u542b\u6709\u4e0d\u540c\u985e\u578b\u7684\u73cd\u8cb4\u5e79\u7d30\u80de\uff0c\u5177\u6709\u5de8\u5927\u7684\u91ab\u5b78\u6f5b\u529b\u3002\u4ee5\u4e0b\u6211\u5011\u5c07\u70ba\u5927\u5bb6\u8aaa\u660e\u4ec0\u9ebc\u662f\u83ef\u901a\u6c0f\u81a0\u8cea\uff0c\u4ee5\u53ca\u5176\u4e2d\u6240\u542b\u7684\u5e79\u7d30\u80de\u5982\u4f55\u7528\u65bc\u6cbb\u7642\u5404\u7a2e\u75be\u75c5\u3002<\/p>\n","protected":false},"author":1,"featured_media":5536,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"inline_featured_image":false,"footnotes":""},"categories":[7],"tags":[],"class_list":["post-5535","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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